Protein Info for BPHYT_RS28540 in Burkholderia phytofirmans PsJN

Annotation: amino acid ABC substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 PF13458: Peripla_BP_6" amino acids 6 to 350 (345 residues), 210.8 bits, see alignment E=4.8e-66 PF13433: Peripla_BP_5" amino acids 7 to 369 (363 residues), 429 bits, see alignment E=1.6e-132

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 100% identity to bpy:Bphyt_5753)

Predicted SEED Role

"Urea ABC transporter, urea binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TGC3 at UniProt or InterPro

Protein Sequence (384 amino acids)

>BPHYT_RS28540 amino acid ABC substrate-binding protein (Burkholderia phytofirmans PsJN)
MALSDPIRVGLLSSTTGSTALLEQSQWRGACLAVEEINARGGIGGRELVALHYDPGSDPA
AFRELAERLIVKDGVNTIFGGYTSTSRKAMLPVVEKHNRLLIYAQMYEGFEYSDNIIYSG
ASPNQNGVQLADFMTETFGARVYFVGSSYVYPYECNRTMQELLLQHPEGAILGERYLSLD
ATRDQFDQVVADIGRKSPDWIFCTVIGETVPYLYEAYARAGLDPASMPIGSLNTSETEIQ
AMQRGIATGHFTAAPYFQSVDTPENHRAVRHHQVRFGAHTPTDMNWEAAYYQMHMFAEAF
ARAGSDELGTIMPHLLGSEFTAPQGRVRIDPVNHHMALYPRIGRVNADGQFTILRESKFA
VGPDPYMTRQTLGDWVTKLSTRDY