Protein Info for BPHYT_RS27425 in Burkholderia phytofirmans PsJN

Annotation: C4-dicarboxylate ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 9 to 28 (20 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 78 to 100 (23 residues), see Phobius details amino acids 151 to 168 (18 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details amino acids 220 to 242 (23 residues), see Phobius details amino acids 261 to 278 (18 residues), see Phobius details amino acids 299 to 319 (21 residues), see Phobius details amino acids 323 to 345 (23 residues), see Phobius details amino acids 352 to 375 (24 residues), see Phobius details amino acids 385 to 404 (20 residues), see Phobius details PF00375: SDF" amino acids 10 to 401 (392 residues), 323.4 bits, see alignment E=1.1e-100

Best Hits

Swiss-Prot: 53% identical to DCTA_LARHH: C4-dicarboxylate transport protein (dctA) from Laribacter hongkongensis (strain HLHK9)

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5522)

MetaCyc: 51% identical to C4 dicarboxylate/orotate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-121A; TRANS-RXN-121C; TRANS-RXN-122A; TRANS-RXN0-451; TRANS-RXN0-517; TRANS-RXN0-553

Predicted SEED Role

"Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate, aspartate"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TGM3 at UniProt or InterPro

Protein Sequence (433 amino acids)

>BPHYT_RS27425 C4-dicarboxylate ABC transporter (Burkholderia phytofirmans PsJN)
MRVAKPLRSLYVQVLLGVVLGIALGHFLPEVGARLRPFSDAFVGLVKMMIAPIVFCTIVS
GITSLASGKAIARTIFQALGLFYLLTAVALALGLVTAFVLQPGAGMHIDAQHLDTSILAQ
YGKHAQPRGLVAFALNVIPETMLGALDKGEVLPVLLLSLLFGFSLNAYPKAGRPVLALID
GIAQTLFRILAMIMRLAPLGAFGAMAFTVGRFGIRSVGSLGMLMVSFYVACLLFVALVLA
PLARLHGFALWRLLRYLREELLIVLATSSTEPVLPRLIAKLEALGCDKGVVGLVLPAGYS
FNLDGTAIYLTLASVFIAQACDVPLTAPQIAIMLAVMLLTSKGAAGVSGSGLVALVATLT
VIPDLPVAGVALLVGIDRFMSEARALTSVISNACAVIFVSMWEGACDRTRLAQMLGAMAP
GGADRSARNTPGT