Protein Info for BPHYT_RS27345 in Burkholderia phytofirmans PsJN

Annotation: aldehyde dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 754 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF20256: MoCoBD_2" amino acids 59 to 186 (128 residues), 80.8 bits, see alignment E=1.3e-26 amino acids 581 to 688 (108 residues), 59.3 bits, see alignment E=4.6e-20 PF02738: MoCoBD_1" amino acids 338 to 471 (134 residues), 59.4 bits, see alignment E=3e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5506)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TGL5 at UniProt or InterPro

Protein Sequence (754 amino acids)

>BPHYT_RS27345 aldehyde dehydrogenase (Burkholderia phytofirmans PsJN)
MSFADDKIDAGRRRFMMSGALVVSFSLIPGIKAMAQEVIADEGAAVHIGKATQALAGSLK
TNPYLDAWIKINATGKVTVYTGKVELGTGVRTALLQIASEELDMAPSLITFLTADTGASP
DEGLTAGSHTIADSGSALLNAAAQVRGLLVDAAAKHFGVSGSAMTVHNAVIRTPDGRAMT
YGEAVGLVDLHRMATPDSPLKDPAKFDMIGTSLPRVDIPAKVTGGPSYVQDMIMPGMVHA
RVVMPPVYDAKLLETNTPEILKMPGVLKVVRNGSLLAVVAKGEWQAVQAQRALAAGSRWS
AGRALPDPATVHRDLKQISTEHIEIANTHNPAGTPVKTLSARYTKRYMMHGSIGPSCSVA
LFKDGEMTVWTHSQGVYPLRDGLAEMLSMPKDKIRCIHVEGSGCYGHNGADDVAAHAALI
AREMDGAPVRVQWMREQEHTWDHFTPAMVTEVRASLDASGTIVDWDYALWSSSHNERIVN
AGRLIPAQMLEKPFVPAPSVPMVQPEGGGDRNAIPLYSFPNMHVMNNFSPAMPLHSSAMR
SLGAHMNVFSIEAIMDELAAAAGADPVAFRLKHLHDPRARDVVQLAARKFGWPRPPRKRN
HGVGFAFGKYKNLMAYVAIAVEVSVVPETGQVILEHAEVAVDSGTIVNPDGIRNQIEGGI
VQSASWTLYEELKFDTSAIRSFDWSSYPILRYSAAPRSIKVHLIDRPGAPFLGAAEASMG
PTAGALANALFDATGKRLRDMPLSGDSLRRQIDV