Protein Info for BPHYT_RS26265 in Burkholderia phytofirmans PsJN

Annotation: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 PF00355: Rieske" amino acids 7 to 91 (85 residues), 61.7 bits, see alignment E=1.8e-20 PF13806: Rieske_2" amino acids 8 to 101 (94 residues), 35.7 bits, see alignment E=2.5e-12 PF07992: Pyr_redox_2" amino acids 119 to 419 (301 residues), 183.6 bits, see alignment E=2.1e-57 PF00070: Pyr_redox" amino acids 265 to 344 (80 residues), 55.6 bits, see alignment E=2.1e-18 PF14759: Reductase_C" amino acids 438 to 505 (68 residues), 35.6 bits, see alignment E=3.9e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_5285)

Predicted SEED Role

"Ferredoxin reductase" in subsystem Anaerobic respiratory reductases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TDD3 at UniProt or InterPro

Protein Sequence (521 amino acids)

>BPHYT_RS26265 FAD-dependent pyridine nucleotide-disulfide oxidoreductase (Burkholderia phytofirmans PsJN)
MPTTARCVAKLSQLRTDRAQRVVVNDEKILLVRDGDTVHAYSADCPHAGAPLEEGALCHG
RIICPWHKGTFDAATGNVLEPPALVGLDRYPVVVTGDDVMVTPEKIPQPARNANAKEPHY
VVIGAGAAGAAACAALRESDFSGRITLVGYEPHAPYDRTALSKFVPSGEMSPVDVPPLLA
PDWLERHDVERIVQKVARLDVPARMIHFENGAALTYDTALLATGSVPKLPHIPGVELGGV
HVLRSLDDAAALVDAIGDDAGQTQVVILGSSFIGLETAAALRKRGTPVTVISPEKVPFAR
QFGERAGAMFRALHERNGVVFHLEAKVASLEGEEGSVHQVMLENGEHVAADIVLLGTGVT
PATGFVEGLPLQKDGGVLVNAGMQAACGLYAAGDIAVFPLHEDQEPVRIEHWRVAQQHAR
IAAQNMCGARHRYAGVPYFWTYHFGKNFEYLGHASEWDEIVTDGDLDRQQFLSLYLKDDK
VVAVLACEREAQTARLIDAMRSGVSRADALAIVGGASCVTK