Protein Info for BPHYT_RS25840 in Burkholderia phytofirmans PsJN

Annotation: acriflavin resistance protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1084 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 331 to 353 (23 residues), see Phobius details amino acids 360 to 380 (21 residues), see Phobius details amino acids 386 to 407 (22 residues), see Phobius details amino acids 431 to 453 (23 residues), see Phobius details amino acids 458 to 483 (26 residues), see Phobius details amino acids 539 to 556 (18 residues), see Phobius details amino acids 902 to 922 (21 residues), see Phobius details amino acids 931 to 949 (19 residues), see Phobius details amino acids 955 to 979 (25 residues), see Phobius details amino acids 1005 to 1025 (21 residues), see Phobius details amino acids 1037 to 1064 (28 residues), see Phobius details PF00873: ACR_tran" amino acids 3 to 1061 (1059 residues), 668.6 bits, see alignment E=7.8e-205

Best Hits

KEGG orthology group: None (inferred from 82% identity to bac:BamMC406_5740)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TCY7 at UniProt or InterPro

Protein Sequence (1084 amino acids)

>BPHYT_RS25840 acriflavin resistance protein (Burkholderia phytofirmans PsJN)
MWIVRLALRRPYTFVVLAVLIFIVGPLAILRTPTDIFPNIDIPVVSIVWSYNGFSAQDMA
SRITSNYERALTSDVDDIEHIESQSLNGVSVVKIFFHPGADINRAIAEAASNSASILRVL
PPGTLPPNIITYNASTVPILQLGLSSDTLSEQQLYDLGNSQIRTQLATVQGASVPLPFGG
KVRQIMVDIDPRALQAKGLAPLDVVNAVNAQNLILPGGTAKIGTKEYNVQMNGSTDTVAA
LNDLPIKTVAGGVVYVRDVAHVRDGYAPQTNIVRSDGKRAALLTIEKSGSTSTLTIIQQV
KAMLPHIAAGLPSALHITALSDQSVFVKSAVVGVAREALIAAALTAVMILLFLGSWRATL
IIAVSIPLAVLTSLIALSALGQTINIMTLGGLALAVGILVDDATVAIENITHHLENGEAL
QDAILNGSGEIAVPTFVSTLSICIVFVPMFLLSGVARYLFVPLAEAVVFAMIASYFFSRT
LVPTLAMYLMRARSNAVATGSGPIARLIRFQAGFEQRFERLRERYRGVLGAAIASPKRFI
AIFLVLCLGSLALVPFTGRDFFPAVDTGEIRLHLRAPTGTRIEDTASITDQVEARVRDVI
PKQELAAVLDNIGVPVSGINLTYDSSDPIGPEDADVMITLAPKHKPTAQYVATLRNTLTK
DFPGVTFAFLPADIVSQILNFGLPAPIDIQIVGNKLDANRAVANRLLAQLRGVRGLVDAR
IQQPGDSPAINVNVDRTRAIQAGLLQRDVSQNLLIALSGSSQTTPNFWLDPRNGVSYPLV
AMMPQYDVNSLQALANIPVAANGDAATVAAAAGMASFPANGTGPAPQNLLGALSTLTRGT
QQAVVSHYNVQPVLDIFASAQGRDLGGVAADVNRLVEQIRPQLPPGASIVVRGQVQAMHD
SFSGLASGLVFAIGLVYLLMVVNFQSWLDPFITISGLPGSLAGIAWMLFSTGTRLSVPAL
TGTILCIGIATANSILVVNTARELHHGGKPPLQAALEAGFSRFRPVLMTALAMLIGMLPM
ALGLGDGGEQNAPLGRAVIGGLALGTVSTLLFVPVVYGMVHAWLDKRRAARSEKHESSVT
ARTL