Protein Info for BPHYT_RS24445 in Burkholderia phytofirmans PsJN

Annotation: type VI secretion protein VasK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1288 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 37 to 57 (21 residues), see Phobius details amino acids 442 to 461 (20 residues), see Phobius details TIGR03348: type VI secretion protein IcmF" amino acids 14 to 566 (553 residues), 456.4 bits, see alignment E=1.3e-140 PF14331: IcmF-related_N" amino acids 190 to 445 (256 residues), 279.2 bits, see alignment E=6.4e-87 PF06761: IcmF-related" amino acids 494 to 846 (353 residues), 261.8 bits, see alignment E=2e-81 PF21070: IcmF_helical" amino acids 1001 to 1088 (88 residues), 41.4 bits, see alignment 2.9e-14 PF06744: IcmF_C" amino acids 1117 to 1220 (104 residues), 89.5 bits, see alignment E=3.1e-29

Best Hits

KEGG orthology group: K11891, type VI secretion system protein ImpL (inferred from 100% identity to bpy:Bphyt_4923)

Predicted SEED Role

"IcmF-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TC67 at UniProt or InterPro

Protein Sequence (1288 amino acids)

>BPHYT_RS24445 type VI secretion protein VasK (Burkholderia phytofirmans PsJN)
MRRILNVLTHTRTLSIIGLLALAAVLFIGADTLQIDLMWPAIVLGAVIALWLLVWIVRRL
RARRANRKLGEMLEQQAEKQAEAGPAPTPARQAELDVLRTRLVDAVKTIKTSKIGQVSGG
SALYELPWYIVIGNPAAGKSSAVLNSGLQFPFADKNNAVIHGIGGTRNCDWFFTTEGILL
DTAGRYSVHEEDRTEWLGFLGLLKRFRPKAPINGIIVTASIAELTSSKPEFAINLAKNLR
QRVQELTEKLEVFAPVYVMFTKADLITGFTEFFSGSERHEYDRVWGATLPYEPDEKRDVV
GLFDEHFEELYDGLKEISVAQMSINRGNKLSPGQLSFPLEFSTIKPALRAFLATLFETNP
FQYKPIFRGFYFTSALQEGETNSAAATRIANRFGLSSDGLPKPHSAFSKNGFFLRDLFSK
VIFADRQTVKQFASPAKTRMRYATFFGFVAVLALALGGWTWSTVNNQQLTANVQADLDNV
VRLQQNRNDLQSRLQAMDVLEDRIDQLEQFRRDRPLAVSLGLYQGDRLEQRLLTEYYNGV
RQILLDPVSQNLASFLKDVNAHPDQLVPLNRAPDAAAIPVSTHSAMSANSQGGLYSDASP
TNVEDAYNALKTYLMLSDKRHVETAHLTDQVARFWRGWLETNRGNMPRDEMIRSAERMIT
FYLARVSDDDWPMIDQNLGLVDQTRENLRRVVRGMPARQRVYEEIKARASTRFAPMTVAR
IVGENNTALVAGSYAIPGTFTREAWFQYVQPAIRDAATKELQAKDWVLNTSAHDDLTLEG
SPEQIQKALVAMYKTEYAMHWQKFMQGIAVQSFGSFGQAVDAMNRLGDPQDSPIRKVLET
AYDQTSWDNPSLFNANLKRAQTGVTSWVKNLFSRAPTGQINANIDINGNPVEVPMGPIGQ
EFSALGRIVVSGDNGSMLKGYMDTLSKVRTRFNVIKNQGDPGPGARQLMQQTLDGSGSEL
ADSLKYVDEQMLTGLTDSQRKALRPLLVRPLMAAYAVVIQPASVEVNKVWNAQVYQSFQN
SLANKYPFASDAKVEAGAGEIAQVFGPDGAIAKFVGTTLGPLAVRRGDTLTARTWGDMGL
ALTPDFTSGFARWVAPLAGGAAGATAGQGSAEPQTVFQILPQPSSGTTEYTLAIDGQQMR
YRNTPPQWTNFVWPNPSGSPGATLSATTFDGRTLQLVNEPGRYGLEKLINSAQRKRRPDG
TFDLSWTQGGVTVAVSMRIISTSQASSGSSDAPQQQSLRGLRLPSSVADVSAAANSVNAT
AAGAPAPATPATRPAAAATAVSNTGGAQ