Protein Info for BPHYT_RS24160 in Burkholderia phytofirmans PsJN

Annotation: D-galactarate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 529 TIGR03248: galactarate dehydratase" amino acids 6 to 529 (524 residues), 924.8 bits, see alignment E=5.8e-283 PF08666: SAF" amino acids 15 to 83 (69 residues), 25.2 bits, see alignment E=3e-09 PF04295: GD_AH_second" amino acids 114 to 276 (163 residues), 113.4 bits, see alignment E=1.3e-36 PF20629: GD_AH_C" amino acids 286 to 525 (240 residues), 309.7 bits, see alignment E=1.9e-96

Best Hits

KEGG orthology group: K01708, galactarate dehydratase [EC: 4.2.1.42] (inferred from 100% identity to bpy:Bphyt_4865)

Predicted SEED Role

"D-galactarate dehydratase (EC 4.2.1.42)" in subsystem D-Galacturonate and D-Glucuronate Utilization or D-galactarate, D-glucarate and D-glycerate catabolism (EC 4.2.1.42)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.42

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TC10 at UniProt or InterPro

Protein Sequence (529 amino acids)

>BPHYT_RS24160 D-galactarate dehydratase (Burkholderia phytofirmans PsJN)
MEQSPLYIRVHPNDNVAIVVNDGGLGEGAVFPDGLALRERVPQGHKVALADLAEGDEVIR
YNVVIGYALKALPKGSWINEHVIRMPSPPGLEDLPIATIKAPDMPPLEGYTFEGYRNADG
SVGSRNILAITTTVQCVADVVQHAVTRIKAELLPRYPNVDDVVSLGHTYGCGVAIDAPDA
MVPIRTVRNISLNPNFGGEVMMVSLGCEKLQPERLMPPGTIPIAAAANVAEVADIGDIEA
DLNGDVVVLQDESHVGFQSMIESIMKMADGHLKRLNNRRRETCPASDLVIGVQCGGSDAF
SGLTANPAVGYATDLLVRAGATVMFSEVTEVRDGVDQLTARAANPEVAAAIIREMQWYDD
YLKRGGADRSANTTPGNKKGGLSNIVEKAMGSIIKSGNSAISGVLSPGEKVKQKGLIYAA
TPASDFICGTLQVAAGINLHVFTTGRGTPYSLAEVPVIKVATRSDLARRWHDLMDINAGT
IATGESTIEEVGWELFRLMLDVASGRKETCAEKLKLHNALTLFNPAPVT