Protein Info for BPHYT_RS22955 in Burkholderia phytofirmans PsJN

Annotation: isoprenylcysteine carboxyl methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 transmembrane" amino acids 42 to 60 (19 residues), see Phobius details amino acids 70 to 88 (19 residues), see Phobius details amino acids 100 to 118 (19 residues), see Phobius details amino acids 124 to 143 (20 residues), see Phobius details amino acids 173 to 195 (23 residues), see Phobius details PF06966: DUF1295" amino acids 126 to 228 (103 residues), 25 bits, see alignment E=1.9e-09 PF04191: PEMT" amino acids 147 to 216 (70 residues), 26.3 bits, see alignment E=1.3e-09 PF04140: ICMT" amino acids 158 to 215 (58 residues), 31.4 bits, see alignment E=3.2e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_4624)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TDF5 at UniProt or InterPro

Protein Sequence (237 amino acids)

>BPHYT_RS22955 isoprenylcysteine carboxyl methyltransferase (Burkholderia phytofirmans PsJN)
MTPTTPLQNQPLAVTTEGATLTGAMPAETGNAGGWREAVVEVAARAGAATMLSLFAYAAI
TQWRAAPSRITLLFLVVSACFTVGLSLVSRVPMRRDWRPFAFLCAMGGTYYFLAVRLAPG
VQLVPEAVGAALQLLGIGWQLFAKASLRRSFGILPANRGVVSRGAYRFIRHPMYLGYFIT
DIGFLLVNFGLQNLLVYGCQFALQVGRIVREERLLSADEGYRTYKRRVRYRVIPGLF