Protein Info for BPHYT_RS22515 in Burkholderia phytofirmans PsJN

Annotation: multidrug efflux RND transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1061 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 369 to 391 (23 residues), see Phobius details amino acids 397 to 419 (23 residues), see Phobius details amino acids 440 to 460 (21 residues), see Phobius details amino acids 472 to 497 (26 residues), see Phobius details amino acids 548 to 568 (21 residues), see Phobius details amino acids 880 to 900 (21 residues), see Phobius details amino acids 907 to 927 (21 residues), see Phobius details amino acids 933 to 956 (24 residues), see Phobius details amino acids 979 to 1000 (22 residues), see Phobius details amino acids 1010 to 1036 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 3 to 1036 (1034 residues), 1190.9 bits, see alignment E=0 TIGR00915: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family" amino acids 4 to 1043 (1040 residues), 1191.9 bits, see alignment E=0 PF03176: MMPL" amino acids 321 to 501 (181 residues), 43.3 bits, see alignment E=3.6e-15 amino acids 884 to 1035 (152 residues), 28 bits, see alignment E=1.6e-10 PF02355: SecD_SecF" amino acids 342 to 498 (157 residues), 22.9 bits, see alignment E=7.7e-09

Best Hits

KEGG orthology group: None (inferred from 88% identity to bac:BamMC406_5229)

Predicted SEED Role

"RND multidrug efflux transporter; Acriflavin resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TDZ1 at UniProt or InterPro

Protein Sequence (1061 amino acids)

>BPHYT_RS22515 multidrug efflux RND transporter permease subunit (Burkholderia phytofirmans PsJN)
MNISKFFIDRPIFAGVLSVLILLAGIISLFKLPISEYPEVVPPSVVVHAQYPGANPKVIA
EAVASPLEEQINGVENMLYMQSQANSDGNLTLTVTFKLGTNPDLATQLVQNRVNQALPRL
PEDVQRLGVTTIKSSPTLTMVVHLISPNNRYDMTYLRNYALLNVKDRLARIQGVGEVQLW
GSGDYAMRVWLDPQKVSQRGLTATEVVNAIREQNIQVAAGVIGASPSVPGTQLQLSVNAR
GRLRTEGEFGDIIVKTTPDGGVTYLKDIARIELAASEYGLRSLLDNKPAVALAINQAPGA
NSLAISDQVRTAMKELAEDMPAGVEYKIVYDPTQFVRSSIEAVVHTLLEAIALVVIVVIV
FLQTWRASIIPLIAVPVSIVGTFSLLLAFGFSINALSLFGMVLAIGIVVDDAIVVVENVE
RNIENGLSARDATYKAMQEVSGPIIAIALTLVAVFVPLAFMTGLTGQFYKQFAMTIAIST
VISAFNSLTLSPALSAMLLRSHGAKEDFLTRVMNRVLGGFFRRFNKVFHRGSTEYGRGVT
GVLRRKGAMLAVYAILLGATVLISRVVPGGFVPAQDKEYLIAFAQLPNGASLDRTEKVIR
DMSSIALKQPGVESAVAFPGLSVNGFTNSSSAGIVFVTLKPFKDRGNKKLSAGAIAGALN
QQYGAIKDSFVAVFPPPPVLGLGTLGGFKMQLEDHGALGYAELNKAAEAFVKKAAQTPEL
GPTFSSYQINVPQLNVDLDRVKAKQLGVPVTDVFNTMQIYLGSLYVNDFNRFGRVYQVRV
QADAPFRQRADDILQLKTRNAAGDMVPLSSLVTVTPTFGPEMVVRYNGYTAADINGGPAP
GFSSGQAQAAAERVAAEVLPHGVKLEWTDLTYQQILAGNAGLWVFPISVLLVFLVLAALY
ESLTLPLAVILIVPMSVLSALTGVWLTGGDNNIFTQIGLMVLVGLSAKNAILIVEFAREL
EHDGHTPLSAAIEASRLRLRPILMTSIAFIMGVVPLVLSSGAGSEMRHAMGIAVFFGMLG
VTLFGLMLTPVFYVVLRTLAGGTIHVAQKDSPHYGAPVTDA