Protein Info for BPHYT_RS21910 in Burkholderia phytofirmans PsJN

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF00497: SBP_bac_3" amino acids 33 to 247 (215 residues), 233.1 bits, see alignment E=4.1e-73 PF10613: Lig_chan-Glu_bd" amino acids 53 to 125 (73 residues), 35.6 bits, see alignment E=1.3e-12 PF12974: Phosphonate-bd" amino acids 118 to 244 (127 residues), 27.7 bits, see alignment E=2.8e-10

Best Hits

Swiss-Prot: 38% identical to GLNH_ECOL6: Glutamine-binding periplasmic protein (glnH) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to bpy:Bphyt_4410)

MetaCyc: 38% identical to L-glutamine ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-12-RXN [EC: 7.4.2.1]

Predicted SEED Role

"Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2)" (TC 3.A.1.3.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TFB5 at UniProt or InterPro

Protein Sequence (251 amino acids)

>BPHYT_RS21910 ABC transporter permease (Burkholderia phytofirmans PsJN)
MKLQRLLSLACVTVAVTFAGFSGAASAQTPDVLNVATDATFPPMEYTENGARTGFDVDLM
NALAKAMGKKVQWTDIDFKGLIPGLIAHRFDAAISGIYITDERAKVVDFTDSYYAGGLVV
LVKSNSPIKSVEELNGKKVSVQVGTKSVNFLRDNFPQINRVEVEKNQEMFDLVGIGRADA
AVTGKPAAYQLVKTRGGFRVLDKPLTTEAYGIAVRKDEPQLKAAFNTALAKIKADGTYAA
IVKKWFGATAQ