Protein Info for BPHYT_RS21515 in Burkholderia phytofirmans PsJN

Annotation: aldehyde dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1207 transmembrane" amino acids 779 to 800 (22 residues), see Phobius details PF20256: MoCoBD_2" amino acids 54 to 181 (128 residues), 79.4 bits, see alignment E=6.8e-26 amino acids 624 to 706 (83 residues), 48.5 bits, see alignment 1.8e-16 PF02738: MoCoBD_1" amino acids 331 to 566 (236 residues), 106.4 bits, see alignment E=2.7e-34 PF00034: Cytochrom_C" amino acids 819 to 917 (99 residues), 26.4 bits, see alignment E=3e-09 amino acids 976 to 1069 (94 residues), 21.9 bits, see alignment 7.6e-08 amino acids 1099 to 1180 (82 residues), 31.3 bits, see alignment 8.9e-11 PF13442: Cytochrome_CBB3" amino acids 1097 to 1178 (82 residues), 38 bits, see alignment 3.4e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_4332)

Predicted SEED Role

"Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16)" in subsystem N-heterocyclic aromatic compound degradation (EC 1.3.99.16)

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.16

Use Curated BLAST to search for 1.3.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TF38 at UniProt or InterPro

Protein Sequence (1207 amino acids)

>BPHYT_RS21515 aldehyde dehydrogenase (Burkholderia phytofirmans PsJN)
MTGPDFSVDRRSAPPSRQQLYDAQSVLIVTRAPQAPVKPAIGQPGSRSSFVPTEADMFLV
VRDDGSVVAFNGHVDLGTGIGTALAQIVAEELDVPLTRVSIVLGHTREAPNQGPTIASAT
IQISAVPLRHAAAQARQFLLAEAAARFNVSVEQLDVRDGVVYRRDGGAAAKGIGYGELIS
GKRVELQLATDAPLKSPDTYKIVGKSTPRVDIPAKATGELSFVHDVRVPGMLHGRVVRPP
YAGVAQGDFMGNSLLQVDEDSVSELPGIVKVVVIRDFVGIVAEREEVAQQAAKRLRVQWK
EVEGLPSLETSEEVEAALRANPAKRRDLVIEGDVDAALAQDSARTLERTYVWPFQMHASI
GPSCAVADYREGALKVWSGTQNPHSLRADLALLMSMDEAHIEIVRMEAAGCYGRNCADDV
AADAALLSRATGSPVRVQLSREDEHAWEPKGAAQLMDVRGALNAEGELAAYDFATRYPSN
DAPTLALLLTGTISAQPQVFEMGDRTAVPPYDYRSMRIVCDDTPPIVRASWLRGVSALPN
TFAHESFIDELAVEAGIDPVEFRLKHLTDPRAIELVKAVAEKAGWEARSAERNAELKDEE
GDIARGRGIAYARYVHSKFPGFGAAWSAWVADVEVNRKSGDLAVTRVVVGQDTGTMVNPD
GVRHQIHGNVIQTTSRALKERVTFGENAVTSQEWGAYPILTFREVPVIDVVMMPRHGEPP
MGAGESASLPGAAAIANALFDATGVRFRRPPFTPETIRAALADAQAEDKAARRKKRWRFG
FLGALAAGAAGWLGALSLAPHAIAPITPPLASAFAPELVARGKLLASLGNCAVCHTAHNG
VPNAGGKPLDTPFGTVYSTNITPDGQTGIGNWSLEAFVRAMRQGISRDGHRLYPAFPYTS
FQNTSDDDLKALYAYLMAQTPVRSHPPETKLAYPFSVRPLMSAWNALFLGRTTFTASTTQ
TAQWNRGAYLVNGLGHCGACHTPRNAFGAEKTGAAFMGGGMADGWEAPALSALSTAPVPW
SEDELFSYLRNGHAPLHGVAAGPMAPVVGDLAALPDSDIRAMATYLASLNPLEPNADPVA
MARQYEQASAISGAPAGLGARLFDGACAACHHTGGGPQLFGAHPSLALNTNLHSATPDNL
IRVILDGIGSPARPELGTMPAYRDSFNDVQVAELVSYLRQQFAGGKPAWQDVAARVARIR
ATPRRAD