Protein Info for BPHYT_RS20910 in Burkholderia phytofirmans PsJN

Annotation: oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01315: Ald_Xan_dh_C
  • amino acids 26 to 138 (113 residues), 67.3 bits, E=2.1e-22
• PF02738: MoCoBD_1
  • amino acids 155 to 380 (226 residues), 205.1 bits, E=1.4e-64
• PF20256: MoCoBD_2
  • amino acids 405 to 683 (279 residues), 194.1 bits, E=5.8e-61

Best Hits

KEGG orthology group: K11177, xanthine dehydrogenase YagR molybdenum-binding subunit [EC: 1.17.1.4] (inferred from 100% identity to bpy:Bphyt_4207)

Predicted SEED Role

"Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR"

MetaCyc Pathways

• purine nucleotides degradation I (plants) (10/12 steps found)
• adenosine nucleotides degradation I (7/8 steps found)
• guanosine nucleotides degradation II (4/4 steps found)
• superpathway of purines degradation in plants (14/18 steps found)
• superpathway of guanosine nucleotides degradation (plants) (5/6 steps found)
• adenosine nucleotides degradation II (4/5 steps found)
• guanosine nucleotides degradation I (3/4 steps found)
• guanosine nucleotides degradation III (3/4 steps found)
• inosine 5'-phosphate degradation (3/4 steps found)
• purine nucleotides degradation II (aerobic) (8/11 steps found)
• ureide biosynthesis (5/7 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• caffeine degradation III (bacteria, via demethylation) (1/7 steps found)
• theophylline degradation (1/9 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (1/10 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.4

Use Curated BLAST to search for 1.17.1.4

Sequence Analysis Tools

See B2TER7 at UniProt or InterPro

Protein Sequence (745 amino acids)

>BPHYT_RS20910 oxidoreductase (Burkholderia phytofirmans PsJN)
MSTLPDSVLSVIGQPQARVDGPLKVSGSATYTSDVNLPDLLIAVPVCSTIASGRLVSLDI
ADAEAMPGVHAVLHRDNIGRFYRLSGNSMETGFVDEARPPFEDDIIRYYGQYIAVVIADT
FEAASAASAAIGARYEVTPHDVRDELEADDKPKVESERGDPNRAFDTAPATLDATYVTPT
ETHNPIELHATIADWDGENYTFYETTQAIAVHLGTLSQMLGVPKEKIRVISRYLGSGFGG
KLWMWPHSLLAAAATRQTGRPVKLVVSRKMMFQNVGHRPVTQQRVRVSAERDGKLTSLQH
DYVNHTAIADDYQESCGEVTPLIYSTPNLRVTSGVTRRNVGSPTSMRGPGAVPGLYAIES
AMNELAHVLNLDPVELRLRNEPRIDESTGLPFSSRHLTECLRMGAERFGWSRRTPGVGSM
QRDGLTLGWGVGACVWPGLRFSAAADVDLRADGSARVVCGTQDIGTGTYTVLAQLVAEET
GIPLERIEVGLGDSVLPLGPISGGSAATASVIPAVLDAVRAATKLLLSRAAAVDGSPFKG
ASEDELAFSAGYVHRKGETPERGVPFGQILEAAKMRAASGSGSAKGGFDDPLKKRFSIYS
YGAHFAEVTWQPEIARLRVSRVVTVIDGGRIVNPRAARNQIEGAVVMGVGMALFEHTMYD
KQTGAPINSNLADYVVATNADTPELDVTFLDHPDTVFNELGARGIAEIGLAGIASAITEA
THHATGVRVRKLPIMIEDLLAAEMT