Protein Info for BPHYT_RS20220 in Burkholderia phytofirmans PsJN

Annotation: antibiotic synthesis protein MbtH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 79 PF03621: MbtH" amino acids 14 to 60 (47 residues), 82.3 bits, see alignment E=6.5e-28

Best Hits

KEGG orthology group: K05375, MbtH protein (inferred from 100% identity to bpy:Bphyt_4064)

Predicted SEED Role

"Hypothetical MbtH-like protein, PA2412 homolog" in subsystem Siderophore Pyoverdine

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TEC7 at UniProt or InterPro

Protein Sequence (79 amino acids)

>BPHYT_RS20220 antibiotic synthesis protein MbtH (Burkholderia phytofirmans PsJN)
MTQAQQTSSAAAGEADDLVYTVVINDEEQYSIWPTFRDVPAGWREVGVRGQKAECLAHIE
TVWTDMRPASLRRHMDAAA