Protein Info for BPHYT_RS19915 in Burkholderia phytofirmans PsJN

Annotation: hemolysin D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 35 to 53 (19 residues), see Phobius details PF00529: CusB_dom_1" amino acids 44 to 438 (395 residues), 29.7 bits, see alignment E=1e-10 PF13533: Biotin_lipoyl_2" amino acids 72 to 120 (49 residues), 36.3 bits, see alignment 7.6e-13 PF13437: HlyD_3" amino acids 75 to 126 (52 residues), 22.6 bits, see alignment 3e-08 amino acids 314 to 429 (116 residues), 44.4 bits, see alignment E=4.6e-15

Best Hits

KEGG orthology group: K02022, (no description) (inferred from 100% identity to bpy:Bphyt_4000)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2TE65 at UniProt or InterPro

Protein Sequence (457 amino acids)

>BPHYT_RS19915 hemolysin D (Burkholderia phytofirmans PsJN)
MKRDSHPRPLSEALEDHSVEGIAILMAEPVRLARALIWAMVALVVVGLLWSFVGRADVIV
SAQGTLSPESEVRRIYAPIDGELADLYIAEGQPVQKGDVLARLNARGAIEAASNALQAQL
KLEDAERDWKQFPEKKALMERKAAALKTQMEVEARQHENRVSEGTTKLAEGQKAELDEAR
SILDNARRTREAARQELDRYSRLFAQPGGGGIAELQVEQKRTAAMEADNAYRVAQSKLAE
LDFRLSHEYTQANAQLETSGQQTTDLQLQYDSAVRDITDAEDKLRLQLQSARLVSEAAAR
IRFENIDKDNFLLILAPVSGVITDVTSTQRGDKIQANAPLGGIAPKDARPVLKIEIAEHD
RAFLHEGLPVKLKFNAFPYQRYGLISGTLAYISPATKPSLTDKQPVYEGRVTLDKNYYQI
ADTRYPLRYGMTASAEIVVRERRLIDLGLDPFRQVAG