Protein Info for BPHYT_RS19720 in Burkholderia phytofirmans PsJN

Annotation: arabinose ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 515 PF00005: ABC_tran" amino acids 41 to 190 (150 residues), 112.5 bits, see alignment E=2.5e-36 amino acids 293 to 444 (152 residues), 79.4 bits, see alignment E=4.1e-26

Best Hits

Swiss-Prot: 79% identical to ARAG_AZOBR: Arabinose import ATP-binding protein AraG (araG) from Azospirillum brasilense

KEGG orthology group: K10539, L-arabinose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to bpy:Bphyt_3961)

MetaCyc: 53% identical to arabinose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-2-RXN [EC: 7.5.2.12, 7.5.2.13]

Predicted SEED Role

"L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2)" in subsystem L-Arabinose utilization (TC 3.A.1.2.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.12 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T7R7 at UniProt or InterPro

Protein Sequence (515 amino acids)

>BPHYT_RS19720 arabinose ABC transporter ATP-binding protein (Burkholderia phytofirmans PsJN)
MTSSHTESHAAQAAPSPALASTEPYLRLDGITVRFPGVLALDQVSLEVRRGEVHGLMGEN
GAGKSTLLKVLSGVNQPAAGTLSLDGVEQQFITTKAAIAAGVAIIYQELHLVPELTVAEN
LMLGALPNRFGILDEKALVARAVRELERLGEKIDPSQQVKNLSIGQRQMIEIGKALMRDA
RVIAFDEPTSSLSSRETTQLFRIIRALKAEGRAIIYVTHRMDEVYELCDRVTVFRDGRRI
DTFEAGEGLDRDRLISCMVGRSIADVYGYRSRDLGDVQLDVKEMMGRGLREPASFTARKG
EIVGFFGLVGAGRSELMKLIYGAVKPDAGEIALKGKRVRFATPRDAVRAGVALCPEDRKQ
EGIVSIASVSDNLNISCRRHFSRFNVLNGRKEAQTAKEFIGKLAIKTRNGDTPIGTLSGG
NQQKVILSRWLAEDIDVFLMDEPTRGIDVGARSEIYGLLYGLAEAGRTVIVVSSDLAEVI
GVADRVIVMKEGRIVGDLPKAQATPDALIKLALPR