Protein Info for BPHYT_RS19605 in Burkholderia phytofirmans PsJN

Annotation: general secretion pathway protein F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 168 to 192 (25 residues), see Phobius details amino acids 223 to 241 (19 residues), see Phobius details amino acids 373 to 398 (26 residues), see Phobius details TIGR02120: type II secretion system protein F" amino acids 4 to 404 (401 residues), 574.8 bits, see alignment E=5.7e-177 PF00482: T2SSF" amino acids 72 to 194 (123 residues), 115.6 bits, see alignment E=7.1e-38 amino acids 274 to 396 (123 residues), 104 bits, see alignment E=2.8e-34

Best Hits

Swiss-Prot: 47% identical to GSPF_PSEAE: Type II secretion system protein F (xcpS) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02455, general secretion pathway protein F (inferred from 100% identity to bpy:Bphyt_3938)

Predicted SEED Role

"General secretion pathway protein F"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T7P4 at UniProt or InterPro

Protein Sequence (405 amino acids)

>BPHYT_RS19605 general secretion pathway protein F (Burkholderia phytofirmans PsJN)
MPAFRFEAIDATGKAQKGVLDADSARGARTNLRSQGLTPLVVEPAATRTRGERNQRLSLG
RRLSQREQAILTRQLASLLIAGLPLDEALAVLTEQSERDYIRELMASIRAEVLGGHSLAN
ALTQHPKDFPEIYRALVAAGEHTGKLGLVLSRLADYIEQRNALKQKIVLAFTYPTIVTII
AFGIVTFLLSYVVPQVVNVFASTKQQLPFLTIMMMALSGFVRNWWWAMLIGVIVLVYLVR
SILRQPGPRLAFDRWLLTAPLLGKLVRGYNTVRFASTLGILTAAGVPILRALQAAAETLS
NNAMRENIDDAIVRVREGTSLSRALGNTKTFPPVLVHLIRSGEATGDVTTMLDRAADGEA
RELERRTMFLTSLLEPLLILAMGGVVLVIVLAVMLPIIELNNLVQ