Protein Info for BPHYT_RS19495 in Burkholderia phytofirmans PsJN

Annotation: choline dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 570 PF00732: GMC_oxred_N" amino acids 17 to 308 (292 residues), 175.5 bits, see alignment E=1.5e-55 PF05199: GMC_oxred_C" amino acids 403 to 541 (139 residues), 143.5 bits, see alignment E=6.8e-46

Best Hits

KEGG orthology group: K00108, choline dehydrogenase [EC: 1.1.99.1] (inferred from 100% identity to bpy:Bphyt_3916)

Predicted SEED Role

"Choline dehydrogenase (EC 1.1.99.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.1.99.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.1

Use Curated BLAST to search for 1.1.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T7M2 at UniProt or InterPro

Protein Sequence (570 amino acids)

>BPHYT_RS19495 choline dehydrogenase (Burkholderia phytofirmans PsJN)
MSYTDTTHATRRLEGEFDYIIVGAGTAGCVLANRLTQDPDVQVLLLEAGGKDDYHWIHVP
VGYLYCIGNPRTDWLYKTQAEAGLNGRALSYPRGRVLGGSSSINGMIYMRGQREDYDEWA
RVTNDASWSWNSVLPVFKRSEDHHAGASESHGAGGPWRVEKQRLKWKILEEFSRAAQETG
IPATDDFNRGDNTGVGYFDVNQKRGIRWNASKAFLRPALKRPNLTVITGAYTQRVVFEGR
RCTGVEYRGDNTDYLAKARCEVILSSGAVNSPQLLELSGIGNGARLQNLGIEVVDDLRGV
GENLQDHLQLRMAYKVDGVRTLNTASAHWWGKLLIGMQYAFFQSGPMSMSPSQLGAFAKS
DPGDRSLTRPDLEYHVQPLSLDRFGEPLHRFNAFTASVCQLRPTSRGSIHIESADASAPP
LIAPNYLSTDYDRHVAANALRLTRRIAAAPALARYRPQEILPGIQYQTEEELQQAAGAVG
TTIFHPVGTCRMGTTDDPGAVVDNRLRVIGVDGLRVVDASVMPTITSGNTNSPTLMIAER
ASDMIREDRRARVGGSFAAQTCATRSMSAV