Protein Info for BPHYT_RS19105 in Burkholderia phytofirmans PsJN

Annotation: aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 PF00155: Aminotran_1_2" amino acids 31 to 289 (259 residues), 35.3 bits, see alignment E=1.2e-12 PF01041: DegT_DnrJ_EryC1" amino acids 33 to 380 (348 residues), 352.4 bits, see alignment E=4.9e-109 PF01212: Beta_elim_lyase" amino acids 56 to 292 (237 residues), 29 bits, see alignment E=1.1e-10

Best Hits

Swiss-Prot: 64% identical to VIOA_SHIDY: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (vioA) from Shigella dysenteriae

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_3836)

Predicted SEED Role

"Aminotransferase, DegT/DnrJ/EryC1/StrS family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T7E3 at UniProt or InterPro

Protein Sequence (385 amino acids)

>BPHYT_RS19105 aminotransferase (Burkholderia phytofirmans PsJN)
MNAALPLRAIESPIESPIDERIYVTQPHLAPLEEFIPYLQQIWDSKVLTNGGPFHQQFEA
ALCKYLGVKHLALFTNGTLALLTALQALRVTGEVITTPYSFVATAHSLVWNGIKPVFVDV
DPDTLNLDPAKIEAAITPQTTAIMPVHCYGKPCDVDAIQKIADNYNLKVIYDAAHAFGVQ
TDTGSVLEHGDLAVLSFHATKVFNTFEGGAIICQDAKTKQRIDHLKNFGFVDETTVVASG
INGKMSEINAAFGLLQLQHIDEALARRAQIDAMYRERLRDIPGIRCMQKAGEKVANHSYF
PILVGPEFPISRDALYQKFRDHDIYARRYFYPLISDFPIYRGLPSAHRENLPIAHAAAQQ
VLCLPIFPALTDGMLERIVGLIADC