Protein Info for BPHYT_RS16920 in Burkholderia phytofirmans PsJN

Updated annotation (from data): L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48)
Rationale: Specifically important in carbon source L-Arabinose; carbon source D-Galactose. Some other dehydrogenases are known to act on both of these substrates.
Original annotation: 3-oxoacyl-ACP reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 PF23441: SDR" amino acids 22 to 212 (191 residues), 32.2 bits, see alignment E=1.9e-11 PF08659: KR" amino acids 26 to 185 (160 residues), 43.9 bits, see alignment E=6.5e-15 PF00106: adh_short" amino acids 26 to 215 (190 residues), 159.9 bits, see alignment E=1.4e-50 PF01370: Epimerase" amino acids 27 to 96 (70 residues), 23.8 bits, see alignment E=7.1e-09 PF13561: adh_short_C2" amino acids 33 to 265 (233 residues), 180.1 bits, see alignment E=1.4e-56

Best Hits

Swiss-Prot: 49% identical to SQD_PSEPU: Sulfoquinovose 1-dehydrogenase (PpSQ1_00405) from Pseudomonas putida

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_3408)

Predicted SEED Role

"Putative oxidoreductase in arabinose utilization cluster" in subsystem L-Arabinose utilization

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.46 or 1.1.1.48

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SYR3 at UniProt or InterPro

Protein Sequence (266 amino acids)

>BPHYT_RS16920  L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (Burkholderia phytofirmans PsJN)
MSSPANANVRLADSAFARYPSLVDRTVLITGGATGIGASFVEHFAAQGARVAFFDIDASA
GEALADELGDSKHKPLFLSCDLTDIDALQKAIADVKAALGPIQVLVNNAANDKRHTIGEV
TRESFDAGIAVNIRHQFFAAQAVMEDMKAANSGSIINLGSISWMLKNGGYPVYVMSKSAV
QGLTRGLARDLGHFNIRVNTLVPGWVMTEKQKRLWLDDAGRRSIKEGQCIDAELEPADLA
RMALFLAADDSRMITAQDIVVDGGWA