Protein Info for BPHYT_RS16740 in Burkholderia phytofirmans PsJN

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 PF01418: HTH_6" amino acids 2 to 75 (74 residues), 78.8 bits, see alignment E=3.7e-26 PF01380: SIS" amino acids 124 to 251 (128 residues), 83.9 bits, see alignment E=1.3e-27 PF13580: SIS_2" amino acids 172 to 208 (37 residues), 28.7 bits, see alignment 1.9e-10

Best Hits

Swiss-Prot: 38% identical to HEXR_ECOLI: HTH-type transcriptional regulator HexR (hexR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_3371)

Predicted SEED Role

"Phosphogluconate repressor HexR, RpiR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SYM7 at UniProt or InterPro

Protein Sequence (281 amino acids)

>BPHYT_RS16740 transcriptional regulator (Burkholderia phytofirmans PsJN)
MMLSQVEEMREQLRPSERKLADYVIEAPREVLDLSMTEVAARAGVSQPTIARFCHALGFS
GFREFKIRLAQGIASGVPTVYRDVRPDEGAPGLIAKVFDRTIGTLIEVRNSLSPDSVEAA
VELLANAARIEFYGAGGSGIAAQDIQHKFFRLGMPSVAYSDPHTYSMSAALLGPGDVVVT
VSNTGRTRDIIEAARSALARGAKVIAITHGSSPLARVASICLFSNVVEENDVFSPMTSRM
SHLAIGDILAVGVALKRGPELVERVGQAKGVIGRLRIDGEG