Protein Info for BPHYT_RS16575 in Burkholderia phytofirmans PsJN

Annotation: Xaa-Pro aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 PF05195: AMP_N" amino acids 14 to 135 (122 residues), 121.6 bits, see alignment E=1.6e-39 PF00557: Peptidase_M24" amino acids 192 to 436 (245 residues), 218.3 bits, see alignment E=9.9e-69

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 100% identity to bpy:Bphyt_3337)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SYJ3 at UniProt or InterPro

Protein Sequence (467 amino acids)

>BPHYT_RS16575 Xaa-Pro aminopeptidase (Burkholderia phytofirmans PsJN)
MNQPTEPTIAIDVYRTRRERVLAALRAAGGGVAIVPTAPEALRNRDADYPYRHDSYFYYL
TGFTEPEALLVLDASAAPGEPASVLFCREKNVERETWEGFRFGPDGAREAFGFDAAFAVA
EIDVQLPRLLADKPSLHYALGASAQLDERVRGWLDAVRAQSRGGVAAPATARDLIPLLDE
MRLIKDDHELAIMRRAGQISAQAHRRAMAACHPGVREYELEAELLYTFRKFGAQAPAYTS
IVAAGANACVLHYPAGNAIAQDGDLILIDAACELDGYASDITRTFPASGRFTPAQRELYD
IVLAAQQAAIDATRAGATFDDPHQAAVRVLSQGLLDTGIIERANFASVDDVIAERAYTPF
YMHRTGHWLGMDVHDVGDYRERGAPRDEAGALPWRTLQTSMTLTIEPGLYIRPTEGVPER
YWNIGIRIEDDAIVTPTGCELMTRDVPVAADEIEALMQEARAAHRGT