Protein Info for BPHYT_RS15285 in Burkholderia phytofirmans PsJN

Annotation: transcription elongation factor GreB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 189 TIGR01461: transcription elongation factor GreB" amino acids 28 to 183 (156 residues), 217.3 bits, see alignment E=4.3e-69 PF03449: GreA_GreB_N" amino acids 30 to 100 (71 residues), 84.4 bits, see alignment E=5e-28 PF01272: GreA_GreB" amino acids 109 to 182 (74 residues), 75.4 bits, see alignment E=2.7e-25

Best Hits

Swiss-Prot: 62% identical to GREB_NEIMB: Transcription elongation factor GreB (greB) from Neisseria meningitidis serogroup B (strain MC58)

KEGG orthology group: K04760, transcription elongation factor GreB (inferred from 100% identity to bpy:Bphyt_3081)

Predicted SEED Role

"Transcription elongation factor GreB" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T6A9 at UniProt or InterPro

Protein Sequence (189 amino acids)

>BPHYT_RS15285 transcription elongation factor GreB (Burkholderia phytofirmans PsJN)
MNKAFVKESSEENDDDLDVAQPDVPAGTKNYITPAGYRRMRDELLHLIDVDRPEVVKLVS
WAASNGDRSENGDYIYGKRRLREIDRRIRFLTKRLDLAEVVDSSKQENVDQVFFGATVEY
ATQDGETHIVTIVGIDEVDLDIGHVSWISPIARALLKAKVGDTVTLYTPAGPQPIDILDV
KYPPPDTGG