Protein Info for BPHYT_RS15045 in Burkholderia phytofirmans PsJN

Annotation: peptidase C26

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 PF07722: Peptidase_C26" amino acids 256 to 465 (210 residues), 184 bits, see alignment E=3.6e-58 PF00117: GATase" amino acids 339 to 467 (129 residues), 62.2 bits, see alignment E=5.3e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_3033)

Predicted SEED Role

"Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)" in subsystem Chorismate: Intermediate for synthesis of PAPA antibiotics, PABA, anthranilate, 3-hydroxyanthranilate and more. or Folate Biosynthesis or Tryptophan synthesis (EC 2.6.1.85)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.85

Use Curated BLAST to search for 2.6.1.85

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T661 at UniProt or InterPro

Protein Sequence (493 amino acids)

>BPHYT_RS15045 peptidase C26 (Burkholderia phytofirmans PsJN)
MSENKPENAGKPGNPTPPSASPAPSGTTPGASIAGSVPPDPAASLPLSHEDAIQSPVKDV
TPPDVASTSTPAAEEAAVRSSTDDPDSASAVTPTDPQKARQRDAAEARSSAAASTARQEA
EVHERDARRAGVHAMRPSPTVGGSEPVDGELVGAVEDVTVNEEIPASAERRAGSPPPGFG
AAPDFTASNPPPPNALPPSPPPRYLKHSDSAWTVFGRIVAARARQIFDRAGQRITQRTLR
IGVSARIFHPEPGAKGLRGKTLQYLEESIAHWVMSRDVLVFMIPTVGHQGMLHPSNIRLR
DYAKHLDGLLLQGGADVSPQSYAEQAASHEWPGDRVRDMYELELLHEFVESGKPVLGVCR
GCQLINVAFGGTLYQDIATDVPTAATHVNENYDQHRHGIHFPDGSTLANMFPGRRDAIVN
SIHHQAVKTLGRDLNIEAVSASDGIIEAVRYRRAPFVMGVQWHPEFHRAGGPELLDCTPL
LDTFLRVARETRF