Protein Info for BPHYT_RS14705 in Burkholderia phytofirmans PsJN

Annotation: peptidase C69

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 PF01523: PmbA_TldD_1st" amino acids 42 to 102 (61 residues), 44.6 bits, see alignment E=2.1e-15 PF19290: PmbA_TldD_2nd" amino acids 129 to 235 (107 residues), 72.9 bits, see alignment E=4.7e-24 PF19289: PmbA_TldD_3rd" amino acids 243 to 455 (213 residues), 240.7 bits, see alignment E=1.6e-75

Best Hits

Swiss-Prot: 48% identical to PMBA_ECO57: Metalloprotease PmbA (pmbA) from Escherichia coli O157:H7

KEGG orthology group: K03592, PmbA protein (inferred from 100% identity to bpy:Bphyt_2965)

MetaCyc: 48% identical to metalloprotease subunit TldE (Escherichia coli)
3.4.24.-

Predicted SEED Role

"TldE protein, part of TldE/TldD proteolytic complex"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T5Z5 at UniProt or InterPro

Protein Sequence (456 amino acids)

>BPHYT_RS14705 peptidase C69 (Burkholderia phytofirmans PsJN)
MAADMDVKQRFFPHTQDELKEIASDILRHAKSLGGTDAATEISEGDGLSVSVRRGEVETI
EHNRDKMVGVTVFIGNKRGNASTSDFSSQALKDTVAAAYNIARFTAEDDCAGLAEAELLE
TAPRDLDLYHPWNLSADEAVEIARRAEDAAFATDPQIKNSEGASVSAQHSQFVLATSRGF
LAGYPYSRHYIACAPIAGSARNMQRDDWYTSTRSAEELADPEAVGRYAAQRALARIGARG
LDTRKVPVLFEAPLAAGILGAFVQATSGGALYRKTSFLVDSLGKPVFAPHVQVVEDPHIA
RAMGSAPFDEEGVRTKQRSVVKDGVVEGYFLSTYSARKLGMQTTGNAGGSHNLSLRSSNT
RPEDDFEEMLRKLGTGLLLTELMGQGVNYVTGDYSRGASGFWVENGKIQYPVEEITVAST
LQEMFHHIVAIGADTITRGTKQTGSVLIERMTIAGQ