Protein Info for BPHYT_RS14290 in Burkholderia phytofirmans PsJN

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 PF01590: GAF" amino acids 27 to 158 (132 residues), 70.1 bits, see alignment E=4.2e-23 PF13185: GAF_2" amino acids 27 to 155 (129 residues), 36.5 bits, see alignment E=8.4e-13 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 163 to 322 (160 residues), 140.3 bits, see alignment E=2.4e-45 PF00990: GGDEF" amino acids 164 to 319 (156 residues), 140.1 bits, see alignment E=8.5e-45

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_2886)

Predicted SEED Role

"FOG: GGDEF domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SZU2 at UniProt or InterPro

Protein Sequence (326 amino acids)

>BPHYT_RS14290 diguanylate cyclase (Burkholderia phytofirmans PsJN)
MHVPPTPTNESARLDTLRALHILDTLPEERFDRLTRLAKRLFGVPIALVSLVDADRQWFK
SCVGLEASETSRDVSFCAHAILGDEILMVPDTLADERFHDNPLVTDNPSIRFYAGCPLTV
PNGSKLGTLCLIDTKPRGLDEEERQLLRDLARMAEQELAAVQLATLDDLTLLSNRRGFEA
LAQHALNVCKRMHKPASLLFFDLNDFKQINDTLGHAEGDRALKTFADVLRTALRESDVIG
RLGGDEFVVLLTDSDSGATQEVTQRLTQMLDARNAEAQRGYHIRYSVGQVQYDCARHQSI
AELLAAADAAMYSHKQASKARAAHRN