Protein Info for BPHYT_RS13750 in Burkholderia phytofirmans PsJN

Annotation: D-2-hydroxyacid dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 PF01565: FAD_binding_4" amino acids 43 to 179 (137 residues), 131.6 bits, see alignment E=1.7e-42 PF02913: FAD-oxidase_C" amino acids 219 to 470 (252 residues), 160.3 bits, see alignment E=7.2e-51

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_2776)

Predicted SEED Role

"D-2-hydroxyglutarate dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SZI2 at UniProt or InterPro

Protein Sequence (472 amino acids)

>BPHYT_RS13750 D-2-hydroxyacid dehydrogenase (Burkholderia phytofirmans PsJN)
MTQTAFLAACRDAIGAAQVLTDPHDTALYLTDWRRRYAGAACAVLCPATPDEVAALVKLA
VEHRIALVPQGGNTGLAGGATPDASGAQAVISLRRLNRVRDIDPHNNTITVEAGVILAEV
QKHADEAGRLFPLSLAAEGSCTIGGNLATNAGGTGVLRYGNARELCLGLEVVTPQGELWD
GLRGLRKDNTGYDLRDLFIGAEGTLGIITAAVLKLHPRPAARVTALAALASPHAALDFLS
LTQRVAGPLLTGFELMSDFCLRLVGRHFEQMRYPFAEPHAQVVLLELSDSESEEHARELF
ERLMETALESGLVQDAVVAENLSQSRAFWNLREHIPLAQAEEGLNIKHDIAVPISRVGHF
IEETDAAIAQAVPGARMVTFGHLGDGNLHYNVQAPEGVDAKAFLTQYQSPINQIVYDSVH
RHRGSISAEHGLGQLKIDEAMHYKQDVEVQLMRAVKRALDPLNLMNPGKVLR