Protein Info for BPHYT_RS13475 in Burkholderia phytofirmans PsJN

Annotation: 2-keto-gluconate dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 528 PF00732: GMC_oxred_N" amino acids 93 to 310 (218 residues), 60.7 bits, see alignment E=1.9e-20 PF05199: GMC_oxred_C" amino acids 396 to 514 (119 residues), 81 bits, see alignment E=1.3e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_2722)

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SY37 at UniProt or InterPro

Protein Sequence (528 amino acids)

>BPHYT_RS13475 2-keto-gluconate dehydrogenase (Burkholderia phytofirmans PsJN)
MDQDNNKVRFSHNDDRVVVIIGSGAGGGTLANELAQKGINVVVLEAGKLHTQGDFTTDEW
GAFQMLSWLDKRTTSGSWRIAKDFPNLPAWICKTVGGTTTHWAGASLRIQPYEFKAKTTY
GDIKDANLLDWPVTREELDPYYDRASQKMGVTRTNGLPGLPGNNNFKVMSAGAMKVGYKD
CNTGHMAINSVVRDDRAHCFQRGFCFQGCRTGAKWSTLYTELPRAQATGHMELRTQAHVV
RIETDARGKAKEVLYYDGNGKLQRQKARVVAVAGNSIETPRLLLNSHSSKFPQGLANGSG
QVGRNYMRHTTGSVYAVFNDKVEMFKGTTMAGIIEDEAVFNPQRGFAGGYHMETVSLGLP
FYAAFLNPGAWGPTFSQAMDQYAYTAGMWIVGEDMPRESNRVTLNTDVKDQYGQPVANVH
FDDHPNDEAMRDHAYKQGTAVYEAAGAKTVYRVPPYPSTHNLGTARMSARAEDGVCNRFG
QTHEVSNLFISDGSQFTTGAAENPTLTIVTLAIRQADHIAGQMNKRAV