Protein Info for BPHYT_RS13285 in Burkholderia phytofirmans PsJN

Annotation: amino acid ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 255 PF00005: ABC_tran" amino acids 17 to 171 (155 residues), 125.6 bits, see alignment E=2.2e-40

Best Hits

Swiss-Prot: 48% identical to TCYC_BACSU: L-cystine import ATP-binding protein TcyC (tcyC) from Bacillus subtilis (strain 168)

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 100% identity to bpy:Bphyt_2684)

MetaCyc: 48% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1)" in subsystem Bacterial Cell Division (TC 3.A.5.1.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21 or 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SY00 at UniProt or InterPro

Protein Sequence (255 amino acids)

>BPHYT_RS13285 amino acid ABC transporter ATP-binding protein (Burkholderia phytofirmans PsJN)
MIRLEKIDKYFGGLRVLNSVDLQLASGNVTALIGPSGSGKSTLLRCVNLLEIPESGSLEL
GDQRLEFSRDHRPSREAVLTIRRRTGMVFQNFQLFPHLTVRQNVMEGLLTVQKWDKDKAR
ARADELLEKVGIAHKADAWPSTLSGGQQQRVAIARALAPSPEVLLCDEPTSALDPGLAAE
VVEVLKQLAVEGMTMLMATHDLRLAATIARDVVFLNNGVVVEAGPSREIFMQPRAPETER
FVSTLTHSLPDEWTQ