Protein Info for BPHYT_RS13020 in Burkholderia phytofirmans PsJN

Annotation: mercuric reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 466 PF07992: Pyr_redox_2" amino acids 6 to 326 (321 residues), 200 bits, see alignment E=1.2e-62 PF00070: Pyr_redox" amino acids 178 to 245 (68 residues), 67.6 bits, see alignment E=2.3e-22 PF02852: Pyr_redox_dim" amino acids 351 to 457 (107 residues), 78.7 bits, see alignment E=7.6e-26

Best Hits

KEGG orthology group: K00520, mercuric reductase [EC: 1.16.1.1] (inferred from 100% identity to bpy:Bphyt_2630)

Predicted SEED Role

"PF00070 family, FAD-dependent NAD(P)-disulphide oxidoreductase" in subsystem Mercuric reductase

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.16.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T5S3 at UniProt or InterPro

Protein Sequence (466 amino acids)

>BPHYT_RS13020 mercuric reductase (Burkholderia phytofirmans PsJN)
MPQHFDAVVIGTGQGGSPLAVRLAKSGRETAVIERAAFGGTCVNVGCTPTKSYVASARAA
HVARHCAELGVQVGGAISVDLAAVKARKDKIIGQSRDGVEAWLRGTQNMSVFKGHARFTG
PRALAISGPDGNLLDEISADEVFINTGTRAVVPPLDGLERIRYYTNSNLLDLTELPSHLV
IVGASYIALEFAQIFRRFGSQVTVLVRGERLLTREDADFADSVQKVLAREGVEFRFNVQP
SRVEPHPHRENEVCVGFEQNIPALEASHLLFATGREPNTDDLGLAAAGIAVDKHGTIPVD
GQLRTNVPGVWAIGDVNGRGAFTHTSYDDYQIVAANLLDGASRSVDTRIMAYAVFVDPPL
ARVGASEAEVRKSGRDALIATMPMTRVGRARERGETDGFMKVMVDKESKRVLGAAIHGIE
GDEALHTFIDIMTADAPYPTLQYAMHIHPTISELVPTLLDGLKPMK