Protein Info for BPHYT_RS12765 in Burkholderia phytofirmans PsJN

Annotation: Co-chaperone protein HscB homolog

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 175 TIGR00714: Fe-S protein assembly co-chaperone HscB" amino acids 18 to 172 (155 residues), 107.2 bits, see alignment E=4.4e-35 PF07743: HSCB_C" amino acids 92 to 166 (75 residues), 67.3 bits, see alignment E=6.4e-23

Best Hits

Swiss-Prot: 100% identical to HSCB_PARPJ: Co-chaperone protein HscB homolog (hscB) from Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)

KEGG orthology group: K04082, molecular chaperone HscB (inferred from 100% identity to bpy:Bphyt_2576)

Predicted SEED Role

"Chaperone protein HscB" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T5L9 at UniProt or InterPro

Protein Sequence (175 amino acids)

>BPHYT_RS12765 Co-chaperone protein HscB homolog (Burkholderia phytofirmans PsJN)
MASLNDSHFDLFDLPAQFALDASALDHAYRTVQAQVHPDRFAAAGDAQKRIAMQWATRTN
EAYQTLRDPLKRATYLLHLRGIDVGAHENTAMEPAFLMQQMEWREGIEDAAAAKNVDALD
ALLTELRDEERMRFDKLGALLDSGANQAAGEAVRQLMFIERVASEIGTQIERLDN