Protein Info for BPHYT_RS12660 in Burkholderia phytofirmans PsJN

Annotation: Hsp33 chaperonin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF01430: HSP33" amino acids 3 to 291 (289 residues), 266.6 bits, see alignment E=1.4e-83

Best Hits

Swiss-Prot: 39% identical to HSLO_PSEFS: 33 kDa chaperonin (hslO) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K04083, molecular chaperone Hsp33 (inferred from 100% identity to bpy:Bphyt_2557)

Predicted SEED Role

"33 kDa chaperonin (Heat shock protein 33) (HSP33)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SXU6 at UniProt or InterPro

Protein Sequence (316 amino acids)

>BPHYT_RS12660 Hsp33 chaperonin (Burkholderia phytofirmans PsJN)
MSDQLQKFMFSAAPVRGEIVSLRNTWQEVLTRRDYPAPVRTVLGEMMAACALLSANLKFD
GTLIMQIFGDGPVKMLVVQCGSDLSMRATAKLSGEAANVIGETASMVDLLNASGHGRCVI
TLDPASKQPGQQPYQSIVPLSGVDGPLNSMAEVLEHYMHHSEQLDTRLWLAANTERAVGM
LLQKLPGDGGIVPHPGDLDADTWERVCTLGGTMSQDELLKEEPETIFRRLFWQENVQHFE
PATARFECTCSREKVGGMLKMLGREEVDGVLEERGHVEIHCEFCNQRYEFDPVDVAQLFV
AEALSQGVTPAAEQRH