Protein Info for BPHYT_RS12220 in Burkholderia phytofirmans PsJN

Annotation: glutathione ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 PF00005: ABC_tran" amino acids 18 to 178 (161 residues), 77.4 bits, see alignment E=4.4e-25 amino acids 336 to 466 (131 residues), 77.6 bits, see alignment E=3.9e-25 PF12848: ABC_tran_Xtn" amino acids 217 to 295 (79 residues), 94.2 bits, see alignment E=1.1e-30

Best Hits

KEGG orthology group: K06158, ATP-binding cassette, sub-family F, member 3 (inferred from 100% identity to bpy:Bphyt_2473)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system ATP-binding protein" in subsystem Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T5L2 at UniProt or InterPro

Protein Sequence (650 amino acids)

>BPHYT_RS12220 glutathione ABC transporter ATP-binding protein (Burkholderia phytofirmans PsJN)
MIRFNQFSLARGTKPLFDNTTFTLNPGEKAGLVGANGAGKSTLFAVLLGELHADGGDFSI
PPNWQIAHVAQETPAADKTALAYTLDGDAALRVIEAAIAAASAAHDGAAEGEAHAAFADA
DGYTAPARAEALLLGLGFTLDQTREPVSSFSGGWRMRLNLAQALMCRSDLLLLDEPTNHL
DLDAIVWLEDWLARYPGTLIVISHDREFLDSVCNVTLHLEQQQIKRYGGNYSQFEVLRAQ
QIALQQSAYEKQQRTVEHLQSYINRFKAQATKARQAQSRVKALEKMELIAPAHASSPFTF
EFRTPDSAPNPMMVMEDVRCGYRSEGEPVVEIPIVDHVMLSIQNGQRIGLLGANGQGKST
LIKTLAGTLEALGGHVREGKGLRIGYFAQHQLETLRPDDTPLQHLARLAPDTREQELRDF
LGSFNFSGEMATSKIAPFSGGEKARLALALIIWQKPNLLLLDEPTNHLDLETRHALTMAL
AQFEGTLILVSHDRHLLRATTDQFMLVAKHRLQEFDGDLDDYRDWLLQHAAEQRAALKAG
AASSGANGGDGADNGVNRKEQRRLEAETRQKLAHLKKPLQSRISKIEKEMDALNAEKATL
DAFVVDPASYEPEQKSKLTEAIRRQADVNARLEALEAEWLETHEELEQIG