Protein Info for BPHYT_RS11825 in Burkholderia phytofirmans PsJN

Annotation: cytosine deaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07969: Amidohydro_3
  • amino acids 47 to 392 (346 residues), 92.4 bits, E=4.9e-30
• PF01979: Amidohydro_1
  • amino acids 53 to 391 (339 residues), 47.9 bits, E=1.2e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_2388)

Predicted SEED Role

"Cytosine deaminase (EC 3.5.4.1)" (EC 3.5.4.1)

MetaCyc Pathways

• pyrimidine nucleobases salvage II (2/2 steps found)
• pyrimidine ribonucleosides salvage III (1/2 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Pyrimidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.4.1

Use Curated BLAST to search for 3.5.4.1

Sequence Analysis Tools

See B2T5C4 at UniProt or InterPro

Protein Sequence (401 amino acids)

>BPHYT_RS11825 cytosine deaminase (Burkholderia phytofirmans PsJN)
MTSSHSSLVISNVRLADGQTVAVSIADGRIAALGPDLAAQPGAVMEDGGGALLLPGFVEG
HTHLDKTNWGRPWYRNEVGATLLDRINNERRWRKESGHDAGAQSLALARAFVQAGTTRLR
THVDVDTDAGLRYLEGVLQTRQTMRDMLDIQIVAFPQSGVLGRPGTDELLERALADGADV
LGALDPALIDGDPVASLNLTFALAERYRKPIDIHLHEPGEVGAFSLKLLLDRVEALGMQG
QVVVSHGFCLGALPERERDVLLERIARLNVALLTSAPPSRPVPPLKICRERGITIFGGND
GIRDTWSPYGSPDMLERAMLIGLRYDMRRDDELAIAFDCVSTAAARGCGFHDYGLHAGAR
ADLVLVDAETIAQAVVARPRRKLVVANGRIVARNGELVAAA