Protein Info for BPHYT_RS11600 in Burkholderia phytofirmans PsJN

Annotation: biotin synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 TIGR03916: putative DNA modification/repair radical SAM protein" amino acids 4 to 393 (390 residues), 552.7 bits, see alignment E=3e-170 PF04055: Radical_SAM" amino acids 61 to 188 (128 residues), 32.4 bits, see alignment E=5.3e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_2338)

Predicted SEED Role

"Radical SAM domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T576 at UniProt or InterPro

Protein Sequence (402 amino acids)

>BPHYT_RS11600 biotin synthase (Burkholderia phytofirmans PsJN)
MELLKKLEVLADAAKYDASCASSGAPKRGSRGTAGLGASTGAGICHSFTPDGRCVSLLKI
LLTNFCLYDCQYCVNRRSSNVPRARFTPEEVVELTLDFYRRNYIDGLFLSSGIIRSSNYT
MEQLVRVAQSLREDHQFRGYVHLKTIPDADPQLIAQAGRYADRLSVNIELPTDSSLARLA
PEKNVRTIKLAMGSIRLAQEEAHSDAKAPKFTPAGQSTQMIVGADQTNDSTILQTAATLY
GAYKLKRVYYSAFSPIPDSPSALPAQAPPLLREHRLYQADFLMRGYGFSADELFEQPGNL
SLDIDPKLAWALAHRDQFPVDLNRAPLRMIARVPGIGMRNAKRLVELRRSRRVRYEDLVR
LRCPLEKIKPFVVTQDYRAALHDTSSARLRRVLAPPVQLALL