Protein Info for BPHYT_RS10065 in Burkholderia phytofirmans PsJN

Annotation: cytochrome C oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 transmembrane" amino acids 30 to 54 (25 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 101 to 121 (21 residues), see Phobius details amino acids 141 to 168 (28 residues), see Phobius details amino acids 182 to 202 (21 residues), see Phobius details PF00510: COX3" amino acids 31 to 201 (171 residues), 95 bits, see alignment E=3.5e-31

Best Hits

KEGG orthology group: K02276, cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 100% identity to bpy:Bphyt_2028)

Predicted SEED Role

"Cytochrome c oxidase polypeptide III (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T4C4 at UniProt or InterPro

Protein Sequence (214 amino acids)

>BPHYT_RS10065 cytochrome C oxidase subunit I (Burkholderia phytofirmans PsJN)
MSDAADLSQTSAQPAEPLPIGSAGERSGGWWGCLTLIATEGALFGYLIFSYLYLASQSTQ
RWPPEGLPKLGLGITNTVILLSSSVFVWLCERCVRRRRLKWAVASMALGVLLGIVFVGIQ
LLEWHDHPYGLTTHLYGSLYFTITGFHMAHVVVGIVVLLFLLLWTALGYFDEKRCAALTI
GGLYWHFVDVVWLFIFSTLYLTPYLFRNLSWPAT