Protein Info for BPHYT_RS09615 in Burkholderia phytofirmans PsJN

Annotation: folate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01571: GCV_T" amino acids 36 to 150 (115 residues), 33 bits, see alignment E=2e-12 TIGR03317: folate-binding protein YgfZ" amino acids 216 to 277 (62 residues), 83.5 bits, see alignment E=4.1e-28

Best Hits

KEGG orthology group: K06980, (no description) (inferred from 100% identity to bpy:Bphyt_1937)

Predicted SEED Role

"Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T434 at UniProt or InterPro

Protein Sequence (357 amino acids)

>BPHYT_RS09615 folate-binding protein (Burkholderia phytofirmans PsJN)
MNIPLATASGTSSGNAVTAAAATPAVLPTLPRPSADEFDAVIHHGAYMPLTQFGVIDATG
DDAASFLHGQLTNDTQHLDAANARLAGYCSAKGRLLASFLTWRSGDTIRLLASKDVQAAV
QKRLSMFVLRAKAKLVDASGELAVIGLAGDVRKALSGVFDALPDGVHVKVDGAAGSLIRV
PDALGHLRFLWIGPKAQVESLLPLLEEKLKRVSPAVWDWLDIRAGEPRITQPVVEQFVPQ
MVNFDVLGAVNFRKGCYPGQEVVARSQYRGTIKRRTSLANVAGELDTVHAGAELFHSDDP
GQPCGMVVNAASAPDGGVDVLVEIKLAALENGSVHLGAAEGPALRFLPLPYGLPTEV