Protein Info for BPHYT_RS09595 in Burkholderia phytofirmans PsJN

Annotation: 2-alkenal reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 PF16884: ADH_N_2" amino acids 6 to 113 (108 residues), 148.2 bits, see alignment E=1.1e-47 PF00107: ADH_zinc_N" amino acids 158 to 288 (131 residues), 74.7 bits, see alignment E=1e-24 PF13602: ADH_zinc_N_2" amino acids 191 to 326 (136 residues), 34.7 bits, see alignment E=4.9e-12

Best Hits

Swiss-Prot: 44% identical to YFMJ_BACSU: Putative NADP-dependent oxidoreductase YfmJ (yfmJ) from Bacillus subtilis (strain 168)

KEGG orthology group: K07119, (no description) (inferred from 100% identity to bpy:Bphyt_1933)

Predicted SEED Role

"Putative oxidoreductase YncB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T430 at UniProt or InterPro

Protein Sequence (332 amino acids)

>BPHYT_RS09595 2-alkenal reductase (Burkholderia phytofirmans PsJN)
MPQINRQLVLASRPQGAVTPDNFRLVETPLAPLADGELRVRNHYLSLDPYMRGRMNDSKS
YAAPQPLDEVMIGGTVGEVVESKNPKFAVGDKVVAMFGWQEYGTSNGTGVQKVDDTHVPL
SAYLGPVGMPGVTAWYGLNRIIVPKAGETVVVSAASGAVGSVVGQLAKLAGARAVGIAGG
ADKCRYVTETLGFDACVDYKAGNLYQDLKAVTPNGVDGYFENVGGAVLDATLARMNAFGR
IALCGFIAGYDGEPVPLKHPSLILTQRLLVQGFIVSEHMDVWPEALKQLGTLVAQKKLAY
RESIAQGLEAAPEAFIGLLKGKNFGKQLVKLI