Protein Info for BPHYT_RS09175 in Burkholderia phytofirmans PsJN
Annotation: 2-dehydro-3-deoxygluconokinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00874, 2-dehydro-3-deoxygluconokinase [EC: 2.7.1.45] (inferred from 100% identity to bpy:Bphyt_1849)Predicted SEED Role
"2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)" in subsystem D-Galacturonate and D-Glucuronate Utilization or D-gluconate and ketogluconates metabolism or Entner-Doudoroff Pathway (EC 2.7.1.45)
MetaCyc Pathways
- Entner-Doudoroff pathway III (semi-phosphorylative) (8/9 steps found)
- D-fructuronate degradation (4/4 steps found)
- 4-deoxy-L-threo-hex-4-enopyranuronate degradation (4/5 steps found)
- D-galacturonate degradation I (4/5 steps found)
- superpathway of β-D-glucuronosides degradation (5/7 steps found)
- superpathway of hexuronide and hexuronate degradation (7/10 steps found)
- 3,6-anhydro-α-L-galactopyranose degradation (4/7 steps found)
- superpathway of microbial D-galacturonate and D-glucuronate degradation (20/31 steps found)
- alginate degradation (1/7 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.45
Use Curated BLAST to search for 2.7.1.45
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See B2T3U6 at UniProt or InterPro
Protein Sequence (312 amino acids)
>BPHYT_RS09175 2-dehydro-3-deoxygluconokinase (Burkholderia phytofirmans PsJN) MTAAPQTGRPEILALGEAMIEFNQSAKDQPNYLQGFGGDTSNFCIAAARQGAQTGFVSAV GADHFGRLLVDLWEREQVDTSLVRVDPQASTGVYFVSHGPNGHAFDYLRAGSAASRYAPH DLPLDAIAAAKVIHLSGISLAISLSACDAALEAIAHARANGVRVSFDTNLRLKLWPLARA RAVMLEAIRQTDICLPSWDDVTDLTGLTGRDEIVDFLLSHGPSVVALKLGKEGSYIATPN ERRVVPGHVVNAVDATGAGDCFGGAFIARIVAGDDPFTAARYANVAAALSTQGYGAVAPI PSRATVEQLLAG