Protein Info for BPHYT_RS09055 in Burkholderia phytofirmans PsJN

Annotation: DNA polymerase III subunit gamma/tau

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 893 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 3 to 355 (353 residues), 426.6 bits, see alignment E=4.3e-132 PF13177: DNA_pol3_delta2" amino acids 20 to 178 (159 residues), 138.2 bits, see alignment E=6.6e-44 PF00004: AAA" amino acids 42 to 171 (130 residues), 39.8 bits, see alignment E=1.5e-13 PF12169: DNA_pol3_gamma3" amino acids 232 to 357 (126 residues), 84.7 bits, see alignment E=1.4e-27 PF12170: DNA_pol3_tau_5" amino acids 762 to 876 (115 residues), 37.1 bits, see alignment E=8.3e-13

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 100% identity to bpy:Bphyt_1826)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T3S3 at UniProt or InterPro

Protein Sequence (893 amino acids)

>BPHYT_RS09055 DNA polymerase III subunit gamma/tau (Burkholderia phytofirmans PsJN)
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
ALNCETGVTSTPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
KVYMIDEVHMLTNHAFNAMLKTLEEPPAHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
GHIVSHLEHILGEEKVPYDAQALRLLARAADGSMRDALSLTDQAIAYSANQVNEEAVRGM
LGALDQSYLIRLLDALADGDGAAVLSVADEMALRSLSFSTALQDLASLLHRIAWAQFAPS
SVLDEWPEAADLRRFAEALSAEQVQLFYQIATIGRSELGLAPDEYAGFTMTLLRMLAFEP
APTGGGGGAAGSARAPGQAGANGAKRAGAPAVAARQGASGLPATAAATPASASSRDASVN
ATAPVRETRPGDAAAVDEGAAVGASVQAAQRANGAIEVPAAVDSIQATLPDSVQGVTTEQ
SPGAEPALVAHEVNPAPLSAVGDAAAASASPATPTAALAPWDDAPTDSAANEASVAAVPN
GSETNDVAAPLDDSAPASSLSAPAAAALARTEQAAAASQESQEPPPAADSAPRRAGGASA
ALDVLRSAGLKVSSDRGRATAAATAKPAAPATPKPAVPRVVVPVPTPGAPRRAPQQDAAP
AASAAPAARTSASSAPAQRNGAEQNGASAPPWDDMPPDEYMPLTAADEGYYGLPDDGYMP
VFDSGPDDVRVNSAAAPAPAPVVDQRPLPAAVPLDPLGFKGDWPALAVDLPLKGISYQLA
FNSELMALEGNTLKLNVPVPQYAEASQVAKLKAALADRLGQTVDVLVEVGPARRTAAAHD
AALRAKRQQEAEREIGADPFVQSLIREFGASIVPGSIRPITPDAGSNGAPSVH