Protein Info for BPHYT_RS07580 in Burkholderia phytofirmans PsJN

Annotation: N-formimino-L-glutamate deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 TIGR02022: formiminoglutamate deiminase" amino acids 10 to 467 (458 residues), 589.6 bits, see alignment E=2.1e-181 PF01979: Amidohydro_1" amino acids 58 to 423 (366 residues), 87.9 bits, see alignment E=4e-29

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 100% identity to bpy:Bphyt_1535)

MetaCyc: 51% identical to formiminoglutamate deiminase subunit (Pseudomonas fluorescens)
Formimidoylglutamate deiminase. [EC: 3.5.3.13]

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T2Y7 at UniProt or InterPro

Protein Sequence (468 amino acids)

>BPHYT_RS07580 N-formimino-L-glutamate deiminase (Burkholderia phytofirmans PsJN)
MTEPHKQSNQSLFAEYAYLRDGWRRNVLLEWDTNGTLTAVTPDTSTPPIGVQKAAGPILP
GMPNLHSHAFQRAMAGLTEYRASGAGATDNFWSWRDLMYRFAARITPEGLASVAQWLYIE
MLKAGYTSVCEFHYVHHTPDGSRYANQAELAQRVVDAASASGIGMTMLPVLYQYSGFGSR
APREDQQRFINTPESLLDLLGTLRAARPETAALRYGVAPHSLRAVSAESLRTLLGGIDNT
APVHIHIAEQTAEVDACVETEGARPVQWLLDRFDIDSRWCLVHATHVDANETLALAKSGA
VAGLCLTTEANLGDGIFPAQEYLDAQGRIGVGSDSHIGVDWRAELRLLEYGQRLARRQRN
VLASAQATHVADRLFAASLEGGAHATGRAVGALQTGRRADWLVLDANHSSIAEHAPNAWL
SGVVFCEHGETPIRDVYAGGDKVVDNRRHRDEEGAYARYRMALADLLK