Protein Info for BPHYT_RS07130 in Burkholderia phytofirmans PsJN

Annotation: biopolymer transporter ExbD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 140 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details PF02472: ExbD" amino acids 14 to 135 (122 residues), 99.4 bits, see alignment E=8.9e-33

Best Hits

Swiss-Prot: 30% identical to TOLR_PSEAE: Tol-Pal system protein TolR (tolR) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03559, biopolymer transport protein ExbD (inferred from 99% identity to bxe:Bxe_A2998)

Predicted SEED Role

"Biopolymer transport protein ExbD/TolR" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T2P6 at UniProt or InterPro

Protein Sequence (140 amino acids)

>BPHYT_RS07130 biopolymer transporter ExbD (Burkholderia phytofirmans PsJN)
MAMSVGQDDNDEVISSINTTPLVDVMLVLLIIFLITIPVVTHTVPVQLPKETIQPLQTTP
KSIVIAVNRDGDFFWNEKQVDAPTLLARLKTVSVMTPQPEVHVRGDQSARYEFIGRVITE
CERAGIAKVSFITEPPARGG