Protein Info for BPHYT_RS05735 in Burkholderia phytofirmans PsJN

Annotation: virulence protein E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 896 PF09397: FtsK_gamma" amino acids 400 to 458 (59 residues), 71.5 bits, see alignment 3.7e-24 PF05272: VapE-like_dom" amino acids 591 to 805 (215 residues), 238 bits, see alignment E=8.1e-75

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_1166)

Predicted SEED Role

"Virulence-associated protein E"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T1X1 at UniProt or InterPro

Protein Sequence (896 amino acids)

>BPHYT_RS05735 virulence protein E (Burkholderia phytofirmans PsJN)
MSTLEQIVLQLAADGHPTLPDGHPIADGKPHRYGAGKKYWYSLHQIERSGEVLGYTGAFG
RWSGNDNGAQPFQWHGEALTQEDVNATRQRQQAAERAEAEKKAQAAKLAANRARDQWHKA
NDDGVSAYLDRKQITPEGVRFDADGTLLVPMFQYTDTIRLVGLQKITPDGAKRFNKGMEK
KGAAYLLGDIGDDDKVAMIAEGYATARSIRMATNDAIPLVICFDAGGILSTARRLRERHP
DLHVLVCADDDWKIEQRLRDCLLEDFGYSGELVPGGDAVRVETRNTWYMLRAEHKQINGG
VEFIELTIWNDVMPERRRRFENAGLKYAYEAVADIGQASVVFPRFADRGDRKLTDFNDLH
CTEGLESVRRQIQSALLAALAPAAEDVPLTALMQDQYLAADPLYDRAVAVVRDAARASVS
LVQRALSIGFNRAARLIERMAVEGIVSDEHPNGTRTVLSIAGVEPATSAGAATDDAPNHD
VENGAHTWERDLARSEKGNLLPTLGNVHLILSNHKAWQGVIAQDDFAGRVMKRKRPPFAQ
GETGEWSDMDDIRCVLWLSQKYGISVRQDIVMNAVLLVADATHFHDVREYLEGVVWDGIE
RVRSWPTRYMKVADSEYVQLAGMKWLIAAVARVMRPGCKADNVLILEGRQGWFKSTALEV
IAGKPWYTNSPIRIGDKDTYAVMAGKWIIELAELDSLNKSDSSAAKSFFATETDRFRNFY
GKRATDVHRQGVFAGSVNFDTYLKDESGNRRYWPLRVGGPILIDDLRRDRDQLWAEAVHL
YRQGVIWHVTEAEKPLFESEQAERYEGDVYEDRIARDLELRGRVTMEEILADILKLDTSK
WTPPEQRRVGKALKSLGWVRKRESTGRREWFYVKEEEVPQPATELITEGADDDAPL