Protein Info for BPHYT_RS05535 in Burkholderia phytofirmans PsJN

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 339 to 360 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 385 to 545 (161 residues), 136.6 bits, see alignment E=3.4e-44 PF00990: GGDEF" amino acids 387 to 543 (157 residues), 125 bits, see alignment E=1.3e-40

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_1128)

Predicted SEED Role

"FOG: GGDEF domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T1J1 at UniProt or InterPro

Protein Sequence (563 amino acids)

>BPHYT_RS05535 diguanylate cyclase (Burkholderia phytofirmans PsJN)
MNRTTLRQATGPVSFMLIVLVCWFVAGMVADRMVQQELDAALRAQRQMSTSIVDNMAEVI
ASDLAMSRAIPATMAEMDVVQRALVQSQNYAVKSGVTEPVLRAALLKDTQMSAVSNFLHD
AQGFSGLDQIWLVNANGVCVASSNSINNPLAAERSFVGTDMRVRGYLTNALLGAFSEAYG
VGRSSGEPGIFIAAPAYADGLLVGVVVAKVGIARLRHWVAHAGTFVADDNGVIIMAHNSE
LEGRALPNSRVSHMTPAERKAIYLRDQIPDIHISVDSQVREQAPWVPSAVAGQLFGMSER
LVPSLYQTRGGLNSGLSAHLVDPLVAWPELLRNHKRDHLLVFLTLAGTVALAWVITVSYV
RERRHHRATRDLAEQLQSANTLLSAEARHDALTGALSRRYFLDLLRHEIERAHAGNEPLC
MAIADLDHFKQINDRFGHAAGDRALEHFVDTCRAELRGADAIGRLGGEEFGLLLPATDLA
GGHEVVERLRLRLKAMPSPKLPASVGLSVSIGITELSPDDLPERIMSRADMALYAAKSGG
RDRTEALPPDDTAPPARTVANVW