Protein Info for BPHYT_RS03995 in Burkholderia phytofirmans PsJN

Annotation: protein tyrosine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 744 transmembrane" amino acids 31 to 51 (21 residues), see Phobius details amino acids 452 to 472 (21 residues), see Phobius details PF02706: Wzz" amino acids 16 to 112 (97 residues), 57.5 bits, see alignment E=2.9e-19 TIGR01005: exopolysaccharide transport protein family" amino acids 17 to 724 (708 residues), 428.8 bits, see alignment E=3.9e-132 PF13807: GNVR" amino acids 394 to 475 (82 residues), 104.4 bits, see alignment E=5e-34 TIGR01007: capsular exopolysaccharide family" amino acids 534 to 729 (196 residues), 141.3 bits, see alignment E=2.9e-45 PF13614: AAA_31" amino acids 553 to 675 (123 residues), 42.2 bits, see alignment E=1.7e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_0820)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2T0D7 at UniProt or InterPro

Protein Sequence (744 amino acids)

>BPHYT_RS03995 protein tyrosine kinase (Burkholderia phytofirmans PsJN)
MAINFENRYTDVSGPDELHLSDYLRTIVRGWRTIVVVTLIALALGCAYAFLAPPTYRADV
LFHVEDKTANANANGKDSLPPLTGMFDTKPSTAAEIELLKSRLVTEETVKKLHLDITATP
RYFPVIGGMIAGLVNGQWGFKLPQFINLSGYAWGDESISVSQFDTSKEMYDATFTLVSGN
DGSYVLRDKNGIAILSGKVGETVQTDTADGPITLRVDKLVGPAGSRFELQRASTLSTVDR
LQKALVVQETTLQSGVIRASLEGGDAGLTAAIVNSMAREFVRQDVESRSTEAEHMLAFLD
QQLPGLRKELDDAEQRYNKFRNTHGTVDLGEESRLLLQQIVDNKTKLMDLQQQRAEMSQR
FTANHPAVAALDAQIAALQGAAANMNRSVAVMPDTEQTALRLLRDVHVDTELYTNLLNSA
QQLRVAKAGQVGNVRVVDFAEAPDEPVRPKRVLAILIALGGGLVLGILLTFFKRAMYGGV
ERPDELEGMLGVPVFAVVPRSQTQLKLQENVMLRRRGLHVLAQQAPEDIAVEGVRNLRTS
LQLSLDHAENNVVMITGSRPDSGKSFLSVNLAALVASANKRVLIIDGDMRRGDVHSHFGV
AHQPGLSDVLSGGDLGSMIQRDVLPGLDVLAKGTLPSHPAELLMSKRFETMLEELKAHYD
LVIIDTPPVLAVTDSTVIGKYAGTTLLVVRHGRHPLNEVMETAKRLRNGGVGLRGVLLTD
VPQEGAFLGSGYQGGYYGYDSIAG