Protein Info for BPHYT_RS02470 in Burkholderia phytofirmans PsJN

Annotation: phosphoserine phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01490: HAD hydrolase, family IB
  • amino acids 5 to 210 (206 residues), 113.6 bits, E=1.5e-36
• TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB
  • amino acids 5 to 199 (195 residues), 62.9 bits, E=3.8e-21
• PF12710: HAD
  • amino acids 6 to 197 (192 residues), 124.8 bits, E=3.1e-40

Best Hits

KEGG orthology group: None (inferred from 100% identity to bpy:Bphyt_0510)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• superpathway of L-serine and glycine biosynthesis I (4/4 steps found)
• L-serine biosynthesis I (3/3 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.3

Use Curated BLAST to search for 3.1.3.3

Sequence Analysis Tools

See B2SWZ1 at UniProt or InterPro

Protein Sequence (227 amino acids)

>BPHYT_RS02470 phosphoserine phosphatase (Burkholderia phytofirmans PsJN)
MSRNLALFDLDHTLLPLDSDQAWAHFIAGLGIEGAARHAQEIDDYYQQYVAGTLDMAAYL
NYTLAPLARHSREQLDTWHAQFMQQVIAPAILPATRALVQRHLDAGDLCCIVTATNVFIT
EPIGKALGFEHLLGIELGTEGGDPLARFTGKAVGTPTFREGKITRTESWLTSLGHRLQDF
PQSWFYSDSINDVPLLERVTNPVATNPDARLRVIATERGWPVIELFA