Protein Info for BPHYT_RS02165 in Burkholderia phytofirmans PsJN

Annotation: adenosylmethionine-8-amino-7-oxononanoate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 TIGR00508: adenosylmethionine-8-amino-7-oxononanoate transaminase" amino acids 22 to 444 (423 residues), 528.2 bits, see alignment E=6.1e-163 PF00202: Aminotran_3" amino acids 32 to 437 (406 residues), 315.9 bits, see alignment E=1.8e-98

Best Hits

KEGG orthology group: K00833, adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC: 2.6.1.62] (inferred from 100% identity to bpy:Bphyt_0447)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SWS8 at UniProt or InterPro

Protein Sequence (453 amino acids)

>BPHYT_RS02165 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (Burkholderia phytofirmans PsJN)
MENPAPPSAVPEDWIARSLRAVWHPCTQMKHHERLPLVPVARGQGAWLYDRAGHRYLDAI
SSWWVNLFGHANPRINAALKDQLDTLEHAMLAGCTHEPAIELAERLGALTNNTLGHAFFA
SDGASAVEIALKMSFHSWRNRGFADKQEFVCIANSYHGETIGALGVTDVALFKDAYDPLI
RHAHVVASPDARLAQPGETAADVARRALDNVRSLFEARAAKIAALIVEPLVQCAAGMAMH
DASYIAGLRALCDQYGVHLIADEIAVGCGRTGTFFACEQAAIWPDFLCLSKGISGGYLPL
SIVLSRDEIFEAFYHDDTARGFLHSHSYTGNPLACRAALATLDLFASDNVLAVNAQKSAK
LRAALAPLAEHKQVRNLRQCGTLFAFDAVLDDAQQAKTFSRRFFENALQRELLLRPISTT
VYLMPPYILDDEELALLAARTRETFEATLAETR