Protein Info for BPHYT_RS00480 in Burkholderia phytofirmans PsJN

Annotation: excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 883 PF17755: UvrA_DNA-bind" amino acids 170 to 282 (113 residues), 45.5 bits, see alignment E=1.7e-15

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 100% identity to bpy:Bphyt_0102)

Predicted SEED Role

"Excinuclease ABC subunit A paralog of unknown function" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B2SZY3 at UniProt or InterPro

Protein Sequence (883 amino acids)

>BPHYT_RS00480 excinuclease ABC subunit A (Burkholderia phytofirmans PsJN)
MPNPSFGESSCTAAASGLVQVRGAREHNLKDVDVNIPRNALVVFSGVSGSGKSSLAFGTL
YAEAQRRYFESVAPYARRLIDQAGVPDVDSIDGLPPAVALQQQRGASNARSSVGSVTTLS
SLVRMMYSRAGAYPAGQPMLYAEDFSPNMPQGACPTCHGLGHVYEVTEAIMVPDPSLTIR
ERAIASWPPAWQGQNLRDILVSMGYDVDRPWKDLPRRDRDWILFTEETPTVPVYAGFTPA
ETRAALKRKLEPSYMGTFTGARRYVLHTFANTQSALMRKRVSRFMEGKPCPTCHGKRLKP
EALSVTFAGVDIGEFMQMPLDQLAALLEPIAQGDFRAHVAGAGTDREATRRDRAERAASG
RAVHSVSPDVRRTSALSEEKRLAAQRLAGGVMARLRQLRGLGLGYLTLDRATPTLSAGEL
QRLRLATQLSSLLFGVVYVLDEPSAGLHPADSQALYDALDRLRDAGNSVFVVEHDLDLMR
RAQWLVDVGPDAGERGGRVLYSGEPDGLRQIAESRTARYLFDEIPAPGSRAREASDWLEL
QGVHRHNLHGVDARIPLGVLTAVTGISGSGKSSLVAQTLPELVLLHLGHEPEDDAAESGT
GEGPAVIEVTGGHLAGDVDAVQRLVQVDQKPIGRTPRSNLATYTGLFDHVRKLFAATPDA
RRRRYDAGRFSFNVAKGRCETCEGEGFVSVELLFMPSVYAPCPTCHGARYNEATLKVLWK
DRNIAEVLQMTVDEASEFFAGEDAVARPLQLLRDIGLGYLRLGQPATELSGGEAQRIKLA
TELQRSQRGRSLYVLDEPTTGLHASDADRLLVQLQRLVDAGNTVVMIEHDMRAVAQADWV
IDVGPGAGDAGGRVVAAGTPPQVAQVPDSRTAPFLAQELARTE