Protein Info for BBR_RS20340 in Bifidobacterium breve UCC2003

Annotation: DNA-binding response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 PF00072: Response_reg" amino acids 7 to 110 (104 residues), 58.7 bits, see alignment E=6.2e-20 PF04397: LytTR" amino acids 140 to 228 (89 residues), 59.8 bits, see alignment E=2.6e-20

Best Hits

KEGG orthology group: None (inferred from 75% identity to bde:BDP_2240)

Predicted SEED Role

"two-component response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (263 amino acids)

>BBR_RS20340 DNA-binding response regulator (Bifidobacterium breve UCC2003)
MHDIRIGVVEDDPAACQRVLDYLNQYRSETGTEFTISVFDDGEQIVEKYTPIYDILFLDI
EMQHMDGMAAARRIRERDDSVVIVFITAAPQYAINGYEVQALSYLLKPVPYFAFRQELKR
SIDMVHRRGSESLLIEASGRQMRVELADVLYIESIRHTIIVHTLSGKLSVSGTLKDFEER
LAEQDFFRSNSCYLVNLRHVVGVEGQDCVMSNGEALRVSRPRKKAFLTTLANYMGAAGPT
SRASTQTAASNKGAAAGSSENED