Protein Info for BBR_RS20330 in Bifidobacterium breve UCC2003

Annotation: PTS sugar transporter subunit IIA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 PF00359: PTS_EIIA_2" amino acids 6 to 143 (138 residues), 81.3 bits, see alignment E=3.4e-27

Best Hits

Swiss-Prot: 32% identical to SGCA_ECOLI: Putative phosphotransferase IIA component SgcA (sgcA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 37% identity to lrh:LGG_00400)

MetaCyc: 32% identical to putative PTS enzyme IIA component SgcA (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (144 amino acids)

>BBR_RS20330 PTS sugar transporter subunit IIA (Bifidobacterium breve UCC2003)
MSYFQPNGMLYVDQVSDWREAVDLVTRPLLDAGTIERGYVDAIKTSIASPGGTYIDLGGG
VALAHARPESGVVSTSLSVLRVGKPFLLADDEDHPINTMFCLAAKDSNAHIDLMQSLALL
LTDSGKLAALNASSNVDELAAALA