Protein Info for BBR_RS20160 in Bifidobacterium breve UCC2003

Annotation: Solute-binding protein of ABC transporter system for sugars

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01547: SBP_bac_1" amino acids 66 to 355 (290 residues), 112.9 bits, see alignment E=3.2e-36 PF13531: SBP_bac_11" amino acids 203 to 363 (161 residues), 29.1 bits, see alignment E=8.3e-11

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 100% identity to bll:BLJ_1994)

Predicted SEED Role

"Multiple sugar ABC transporter, substrate-binding protein" in subsystem Fructooligosaccharides(FOS) and Raffinose Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-positive bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>BBR_RS20160 Solute-binding protein of ABC transporter system for sugars (Bifidobacterium breve UCC2003)
MRIERTAKTVIAGLMSVACLASVAACGPGSSSNKANTETEAVSTDLGDTKYELKLWDGAG
LKTFDDQLIEAFQKKYPNITIKATYDPDNTSQQNGPRIISAADTPDIARITDINSAVRGN
HVVNLDAYADAYGWKLPDSQTQVYRVGSDGKIGSGSLYAVPDGVSMTGLYWNKKVAKELG
ITEAPATVEELEADMKKASDAGKLAMMMPAKEGGTSYIYQALLTNYEGRDTVQDWIIQKD
GATFNTDGAVKAAQKIKDWQDAGYFSSDALALDGSTALSRFCNGEALFFPSGSWYSASIN
DALGDDAGWIAFPGEKADSGSAAANAVTAFGIPANAKNKNAAAAFLDFLQSDEARQIAVD
NGYPPVGEGETPSTDNQLLGQVLTAYEGLVKTGNTTDYINNATAGMQASAIIPGFQSLID
GTMTPKAFVESIQAQYEKEAK